iHuman Case Study – Appendicitis
Two diagnostic questions and one about examination technique. The third is the one that separates a case write-up from a diagnosis you happened to reach.
Editorial process
Last reviewed · August 25, 2026
The examination question is not a formality
The differential list is supplied, which shifts the work from generating it to justifying each entry and then excluding it. Appendicitis, acute pancreatitis, peptic ulcer disease and small bowel obstruction all present with abdominal pain and each is distinguished by features the case either contains or does not: the migration of pain from periumbilical to right lower quadrant and anorexia point toward appendicitis; epigastric pain radiating to the back with elevated lipase points toward pancreatitis; pain related to meals with a history of anti-inflammatory use points toward ulcer disease; and colicky pain with vomiting, distension and absent flatus points toward obstruction. Say why each was considered and what excluded it, since a differential without exclusions is a list rather than reasoning. Working the list this way also produces the supporting findings the second question asks for, since what excludes one diagnosis frequently supports another. A differential without exclusions is a list rather than reasoning.
The third question is about examination technique and it rewards precision. Auscultation comes before palpation in the abdomen, which is the reverse of the usual sequence and the reason is that palpation alters bowel sounds; normal bowel sounds are irregular gurgles several times a minute in all quadrants, while high-pitched tinkling and rushes suggest obstruction and true absence requires several minutes of listening before it can be called. On palpation, a soft abdomen tender only on deep palpation is different from involuntary guarding and rebound tenderness, which indicate peritoneal irritation and change the urgency. Naming the classical localising signs, and noting that each has modest sensitivity on its own, is what makes the answer clinical rather than a recitation. Finish by saying which findings would change your management rather than only your diagnosis. The classical signs each carry modest sensitivity alone, which is why they are read together.
Likely learning objectives
- Justify and then exclude each supplied differential.
- Explain why auscultation precedes palpation in the abdomen.
- Distinguish deep tenderness from guarding and rebound.
- Treat localising signs as modestly sensitive rather than decisive.
Assignment instructions
Read the full question
Review every instruction before using the planning guidance that follows.
Assignment iHuman Case Study – Appendicitis iHuman Case Study – Appendicitis Reserved For Expert_ Researcher 1- What is your list of appropriate differential diagnoses and why? list of appropriate differential diagnoses for Jerome Cauthen’s case. × appendicitis × pancreatitis, acute × peptic ulcer disease × small bowel obstruction 2- What is the final diagnosis and what assessment findings serve to support this? Appendicitis 3- What are the specific auscultation palpation findings of the abdomen that are normal versus abnormal?
What the case asks
- 01A list of appropriate differential diagnoses and why.
- 02The final diagnosis and the assessment findings supporting it.
- 03The specific auscultation and palpation findings of the abdomen that are normal versus abnormal.
- 04Reasoning consistent with the case material provided.
Differentials, diagnosis, examination
The presentation
Summarise the history and the findings that matter diagnostically.
What the assessor is likely looking for
Findings selected for diagnostic value.
Working the differentials
Justify each of the four and state what excludes it.
What the assessor is likely looking for
Exclusion reasoning present.
The final diagnosis
State it and assemble the supporting findings.
What the assessor is likely looking for
Support from the case's own data.
Auscultation
Describe normal and abnormal bowel sounds and the sequence rule.
What the assessor is likely looking for
Technique with its rationale.
Palpation
Distinguish tenderness, guarding, rebound and localising signs.
What the assessor is likely looking for
Signs distinguished by what they indicate.
What would change management
Identify findings that alter urgency rather than diagnosis.
What the assessor is likely looking for
Management consequences named.
Where the clinical evidence sits
Recommended databases
- NCBI Bookshelf
- MedlinePlus
- PubMed Central
- American College of Gastroenterology
Search sequence
- 1.Read the appendicitis overview for presentation and localising signs.
- 2.Check the differentials individually for their distinguishing features.
- 3.Look up abdominal examination technique for the sequence and findings.
- 4.Find sensitivity and specificity data for the classical signs.
Reference shortlist
These are authoritative starting points, not a ready-made bibliography. A qualified reviewer must confirm that each source fits the assignment and supports the claim beside which it is cited.
Appendicitis
StatPearls, NCBI Bookshelf · 2023
Appendicitis, for presentation, examination findings and diagnosis.
Peptic Ulcer Disease
StatPearls, NCBI Bookshelf · 2023
Peptic ulcer disease, for one of the supplied differentials.
Small Bowel Obstruction
StatPearls, NCBI Bookshelf, US National Library of Medicine · 2023
Small bowel obstruction, for the obstruction differential and its signs.
Evaluation and Management of Mechanical Small Bowel Obstruction in Adults
Agency for Healthcare Research and Quality, NCBI Bookshelf · 2022
Evaluation and management of mechanical small bowel obstruction, for the examination findings.
Peptic Ulcer Disease
American College of Gastroenterology · 2025
Peptic ulcer disease overview, for the meal-related pain pattern.
Before you submit
Common mistakes
- Listing differentials without saying what excludes each.
- Palpating before auscultating in the described sequence.
- Calling bowel sounds absent after a brief listen.
- Treating a single localising sign as diagnostic.
- Answering the examination question in general terms.
Submission checklist
- Does each differential have a reason for inclusion and exclusion?
- Is the final diagnosis supported by named findings?
- Is the examination sequence stated correctly with its rationale?
- Are normal and abnormal findings distinguished for both techniques?
- Is the sensitivity of localising signs acknowledged?
Use this guide to plan and review your own work. Follow your institution's rules and read Brinevia's academic-integrity policy.
Written by
Maren Caldwell
MSN, RN, CNE
Medical-surgical nursing, pharmacology and NCLEX preparation
Maren is a registered nurse with over 15 years of clinical and educational experience in medical-surgical nursing. She writes on NCLEX preparation, patient care fundamentals, pharmacology and evidence-based practice.

Reviewed by
Dr. Tessa Redmond
DNP, RN, CNE
Evidence-based practice and clinical education
Tessa is a doctorally-prepared nurse educator. She reviews Brinevia content for clinical accuracy and alignment with current evidence-based guidelines.